Publications

Description of gen. nov., sp. nov., isolated from human faeces, which forms a distinct branch in the order , and proposal of fam. nov.

Jan 2, 2019

 

Masami Morotomi, et al.

 

A novel, strictly anaerobic, non-motile, non-spore-forming, Gram-negative, short, straight rod with tapered ends, designated YIT 12065, was isolated from human faeces. Strain YIT 12065 was saccharolytic and negative for catalase, oxidase and urease, hydrolysis of aesculin and gelatin, nitrate reduction and indole production. The end products of glucose fermentation were acetic acid and a small amount of butyric acid. The DNA G+C content was 51.3 mol%. The predominant fatty acids were iso-C, C and C. Respiratory quinones were not detected. The cell wall contained glutamic acid, serine, alanine and -diaminopimelic acid. The whole-cell sugars were ribose, rhamnose, galactose and glucose. Phylogenetic analyses based on 16S rRNA gene sequences using three treeing algorithms revealed that the strain formed a novel family-level lineage within the phylum , class , order . JW/HY-331 was shown to be the closest named relative on the basis of 16S rRNA gene sequence similarity (86.9 %), followed by DSM 14871 (86.3 %) and JCM 13193(86.1 %). Similar 16S rRNA gene sequences (98.6–96.7 %) were found amongst faecal uncultured clones of human and dugong (). They clustered with strain YIT 12065 in a distinct and deep evolutionary lineage of descent in the order . The distinct phylogenetic position supports the proposal of gen. nov., with the type species sp. nov. (type strain YIT 12065  = DSM 22607  = JCM 16072). A new family fam. nov. is also proposed.

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